Frequency assignment problems are NP-complete.An immune genetic algorithm is proposed to solve them

which is based on the immune regulation mechanism.Its structure is similar to genetic algorithm.The kernel idea is to construct an antibody network with all individuals

to regulate individual diversity with immune density regulation mechanism at the individual level

and to regulate the balance between individual diversity and population convergence at the population level with immune network regulation mechanism.Therefore

this algorithm can avoid some deficiencies of standard genetic algorithm.We solved both the fixed frequency assignment and the minimal span frequency assignment and got better results.