BioAgent:a Biological Data Integration System Based on Multi-Agent

ZHUANG Yong-long; MA Fei; ZHOU Min; SHEN Yan; LI Yan-da

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BioAgent:a Biological Data Integration System Based on Multi-Agent

更新时间：2025-07-16

- BioAgent:a Biological Data Integration System Based on Multi-Agent
- Acta Electronica Sinica Vol. 33, Issue 1, Pages: 78-82(2005)
- 作者机构：
  
  1. 清华大学生物信息学研究所教育部生物信息学重点实验室,北京,100084
  2. 中国协和医科大学基础医学院 100005,国家人类基因组研究中心,100176
  3. 清华大学生物信息学研究所教育部生物信息学重点实验室北京,100084
  4. 中国协和医科大学基础医学院 100005国家人类基因组研究中心,100176
- 作者简介：
- 基金信息：
- DOI：
  CLC： Q811.4
- Published：2005
- 稿件说明：
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ZHUANG Yong-long, MA Fei, ZHOU Min, et al. BioAgent:a Biological Data Integration System Based on Multi-Agent[J]. Acta Electronica Sinica, 2005, 33(1): 78-82.
DOI：

ZHUANG Yong-long, MA Fei, ZHOU Min, et al. BioAgent:a Biological Data Integration System Based on Multi-Agent[J]. Acta Electronica Sinica, 2005, 33(1): 78-82. DOI：

摘要

随着人类基因组计划的实施

生命科学研究已进入后基因组时代.人们基于指数形式增长的核酸、蛋白质序列和结构等数据

开发了数百种不同类型的数据库.由于不同数据库存贮和检索方式的极大差异

给研究者对它们的整合应用造成了一定的难度.本文建立了一个基于多Agent的生物信息数据整合系统-BioAgent

通过信息采集Agent、信息整合Agent、用户Agent的协调

完成数据抽取、数据标准化、数据存储、数据融合、Web显示等工作流程

以实现数据整合的自动化.同时利用BioAgent系统

开发了人类精神分裂症相关基因的突变信息多层次定位数据库.

Abstract

With the exponential growth of biological data

there exist several challenges to effectively using such information for further research.Biological data are often complex

heterogeneous

hierarchical and dynamic

and may need to be integrated.We developed a software system

namely BioAgent

based on Multi-Agent system and XML technology for data integration

querying and customization.BioAgent consists of Information Extraction Agent

Intelligent Integration Agent

User Interface Agent and Information Customized Agent.We also developed a database of variants located on several levels based on BioAgent system.

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