The development of nano-biosensors and terahertz technology can meet the requirements of high-speed and reliable transmission of lung medical data to telemedicine institutions. Therefore

intra-body terahertz nanosensor network has great application prospects in remote lung health monitoring. Considering the limited energy of the nanonodes and the strict latency requirements for data transmission

a low-delay low-energy consumption (LDLE) topology model is proposed. The model aims at minimizing the total network delay and energy consumption

and transforms the topology design problem into a mixed integer nonlinear programming model solution problem and solves the optimal goal. The result shows that the mesh network topology has low network delay

high throughput and long network lifetime

which can meet the requirements of low energy consumption and low delay of lung terahertz nanosensor network.