The disturbances caused by the instability of probe hold and the breathing exercise from subjects

are introduced during B-ultrasound examination.It decreases the measuring accuracy of the arterial wall displacement obtained from the B-Mode images by speckle tracking method.Thus

we propose a global rigid-registration method based on phase images of B-Mode images to eliminate these external disturbances.The phase features are obtained from B-Mode images via Riesz transform and difference of Gaussian filters.To improve the speed of searching optimization and the registration accuracy

a stepwise registration method is applied based on position weighted principal axis and centroid method combined with mutual information.The results show that

compared with these schemes of extracting wall displacement directly from B-Mode or phase images by speckle tracking method

this scheme can effectively remove these disturbances

and significantly improve the estimation accuracy.The proposed method can also be used in image registration of cardio-cerebro diseases.