1. 中国科学院电子学研究所传感技术国家重点实验室,北京,100080
2. 中国科学院研究生院,北京,100039
3. 中国科学院电子学研究所传感技术国家重点实验室北京,100080
4. 中国科学院研究生院北京,100039
纸质出版:2007
移动端阅览
魏金宝, 杨海钢, 韩泾鸿, 等. 新型的ISFET微传感器读出电路单芯片集成研究[J]. 电子学报, 2007,35(2):224-227.
WEI Jin-bao, YANG Hai-gang, HAN Jing-hong, et al. Monolithic Integration of a Novel ISFET Microsensor Readout Circuit[J]. Acta Electronica Sinica, 2007, 35(2): 224-227.
生化微传感集成系统是目前的研究焦点
本文以在线性区和饱和区两种模式下工作的pH-ISFET作为研究对象
提出ISFET微传感器与其信号读出电路的单芯片集成
并深入研究传感机理以及与标准CMOS兼容的敏感材料制备技术.整个芯片包含ISFET/REFET微传感差分对、双模式ISFET/REFET放大器、次级差分放大、参比电极Pt、恒流源等
采用新加坡Chartered半导体集成电路公司3.3V标准CMOS工艺流片.同时进行传感器芯片的pH响应实验测试
获得53mV/pH灵敏度.
Integration of ISFETs in biochemical SOC (System on a Chip) is one of today’s challenges.This article presents a full integration of micro-sensor and readout circuit containing ISFET/REFET (reference FET) pair
ISFET/REFET amplifiers
bias current generator
band-gap reference
as well as a reference electrode structure
all integrated on the same chip based on CMOS technology.The sensor chip is fabricated in a standard 0.35μm CMOS process (Chartered Semiconductor
Singapore) and operates at 3.3V.The extra post processing steps have been developed for ISFET which can work in either linear or saturation region by programmable control.Finally pH response experiments have been carried out and the measurement system achieves 53 mV/pH sensitivity and the enhanced linearity.
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