WANG Yu, RAO Ni-ni, KUANG Bin, et al. Predicting Protein Coding Regions of DNA Sequences Based on Wavelet Translation Technique[J]. Acta Electronica Sinica, 2007, 35(1): 141-144.
WANG Yu, RAO Ni-ni, KUANG Bin, et al. Predicting Protein Coding Regions of DNA Sequences Based on Wavelet Translation Technique[J]. Acta Electronica Sinica, 2007, 35(1): 141-144.DOI:
The major signal in protein coding regions for most of genomic sequences is three-base periodicity.In this paper
we analyze this periodicity using wavelet transformation (WT) and propose a novel prediction approach for the protein coding regions of DNA sequences based on WT.This approach is able to predict and locate the coding regions simultaneously and is independent of training sets or existing database information.The validity of this approach is verified by a great deal of research results from theoretical analysis and experiments.The sensitivity and the specificity of novel approach reach 81% and 75% respectively.So
the prediction effectiveness is good.Especially
the sensitivity of novel approach is greatly improved compared with other techniques currently in use.