The most one critical component in innate immune system is dentritic cell (DC)

which differentiation mechanism is also the key to initiate and control adaptive immune response correctly.Firstly

based on describing biological principles of DCs differentiation

the information processing procedure for DCs is abstracted.Secondly

laying the foundation of illustrating four-category behavioral signals such as danger-associate molecular patterns et al.

and informational fusion procedure

agents including immature

fully mature and semi-mature DCs are defined

and detailed mathematical differentiation model are formulized and deducted.Lastly

several relations between quantity and lifecycle of different Agent category are proved.Simulation testing results demonstrate that DCs differentiation mechanism has theoretical significance and practical value on computer security besides decreasing false positive rate as well as achieving homeostasis for intrusion detection systems.