How to avoid the various undesired hybridizations is a crucial problem in DNA based computing and other microarray applications.In order to achieve reliable hybridization

we should explore reliable and robust encoding methods.The single template method proposed by Arita can achieve a promising shift distance with l/3 between DNA strands.However

the limited codes produced by it cann’t meet the requirement of any practical application because only one possible template is employed.We extend it to multiple templates case so that the final codes can be linearly increased with the number of the templates while still keeping a shift distance close to l/3.Thus

the improved method can be applied to larger applications.