Based on the sequential quadratic approximation medel of circuit characteristics functions
a new statistical optimization technology is given in which the random fluctuation of circuit performance is considered.Because of the specialities during IC design and manufacture
the method solves parameter optimal problem
of which design space and fluctuation space are different.In this paper
the theoretic framework of this model is obtained.The feasibility and utility of the method are demonstrated satisfactorily by an example of CMOS design at last.