ECG base-line drift cancellation is an important problem.This paper uses segmenting 3-order Hermite interpolation for base-line drift correction

and presents a linear transformation rules of interpolation basic functions when the signal length of interpolation interval changes owing to the changing of heart rate.This correction technique has higher precision of approaching and less amount of computing

and it can be used for real-time ECG monitor. In addition

this paper presents a design of hardware circuits for computing the Hermite interpolation function

and the time for computing one point is only 12μS.