一种基于Transformer架构的多层级自动睡眠分期模型

金峥; 贾克斌

doi:10.12263/DZXB.20240596

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一种基于Transformer架构的多层级自动睡眠分期模型

学术论文 | 更新时间：2025-12-08

- 一种基于Transformer架构的多层级自动睡眠分期模型
- A Hierarchical Automatic Sleep Staging Model Based on Transformer Architecture
- 电子学报 2025年53卷第2期页码：545-557
- 作者机构：
  
  1.北京工业大学信息科学技术学院，北京 100124
  2.先进信息网络北京实验室，北京 100124
  3.计算智能与智能系统北京市重点实验室，北京 100124
- 作者简介：
  
  [ "金峥男，1997年3月出生于北京市.2019年获得北京工业大学信息学部电子信息工程专业学士学位.目前在北京工业大学信息科学技术学院电子科学与技术专业攻读博士学位.主要研究方向为时序信号处理（主要为生物医学信号）、机器学习、数据挖掘.E-mail: zhengj@emails.bjut.edu.cn" ]
  [ "贾克斌男，1962年8月出生于新疆维吾尔自治区乌鲁木齐市.分别于1990年和1998年获得中国科技大学信息与通信工程专业工学硕士学位和博士学位.现为北京工业大学信息科学技术学院教授、博士生导师，并担任数字多媒体信息处理与成像技术研究团队领导人.主要研究方向为数据挖掘、模式识别、信号处理、机器学习、生物信息处理等. E-mail: kebinj@bjut.edu.cn" ]
- 基金信息：
  
  北京市自然科学基金(4212001)
- DOI：10.12263/DZXB.20240596
  中图分类号： TP391;
- 收稿：2024-06-25，
  
  修回：2024-10-28，
  
  纸质出版：2025-02-25
- 稿件说明：
移动端阅览
金峥, 贾克斌. 一种基于Transformer架构的多层级自动睡眠分期模型[J]. 电子学报, 2025, 53(02): 545-557.

JIN Zheng, JIA Ke-bin. A Hierarchical Automatic Sleep Staging Model Based on Transformer Architecture[J]. Acta Electronica Sinica, 2025, 53(02): 545-557.
金峥, 贾克斌. 一种基于Transformer架构的多层级自动睡眠分期模型[J]. 电子学报, 2025, 53(02): 545-557. DOI：10.12263/DZXB.20240596

JIN Zheng, JIA Ke-bin. A Hierarchical Automatic Sleep Staging Model Based on Transformer Architecture[J]. Acta Electronica Sinica, 2025, 53(02): 545-557. DOI：10.12263/DZXB.20240596

摘要

睡眠是人体保持健康的重要生理过程，基于多导睡眠图（PolySomnoGraphy，PSG）的睡眠分期是诊疗睡眠疾病和评估睡眠质量的重要依据.人工睡眠分期法在处理大规模PSG数据时存在耗时久、效率低的问题，采用深度学习模型有效表征PSG的自动睡眠分期法显现出广阔的研究前景.针对现有模型未充分考虑PSG片段内波形信息、通道间相关性信息、片段间睡眠转换信息的问题，本文提出一种基于Transformer架构的多层级睡眠分期网络模型（Hierarchical transFormer sleep staging model，HierFormer），采用Transformer编码器有效提取片段内波形特征、通道相关性特征、片段间转换特征，并结合注意力机制综合提升模型对于PSG片段内、通道间、片段间三种视角信号特性的可解释性.基于睡眠集-欧洲数据格式（sleep-European Data Format，sleep-EDF）扩展睡眠数据集开展的实验结果表明：本文模型利用更少的参数量取得优于多种现有基线模型的分期性能，分类准确率、宏平均精确率、宏平均召回率、宏平均F1分数、科恩卡帕系数分别可达到0.807、0.784、0.735、0.750和0.721.通过在三种视角下不同特征编码方式的性能对比和注意力分数的可视化，本文进一步证明了所提模型良好的编码能力和可解释性.本研究旨在为睡眠分期领域的深度学习应用提供新途径和新技术，从而辅助医生提升睡眠疾病诊疗效率.

Abstract

Sleep is the significant physiological process to keep healthy. Sleep stage classification based on polysomnography (PSG) is the fundamental evidence to diagnose sleep disorders and assess sleep quality. Manual sleep staging method has some typical problems when handling the large-scale PSG data

such as time-consuming and low-efficiency. The automatic sleep staging method that utilizing deep learning models to effectively learn PSG representations shows extensive researching prospects. Most existing models cannot fully consider the epoch-level waveform information

channel-wise correlations

sequence-level sleep transitions. This paper proposes a transformer-based hierarchical sleep staging model (HierFormer)

which employs transformer encoder to extract valid epoch-level waveform features

channel-wise correlation features

sequence-level transition features. Meanwhile

it adopts attention mechanism to improve the model interpretability of signal properties from three views

including epoch-level

channel-wise

and sequence-level views. Experimental results on the sleep-european data format (sleep-EDF) database expanded dataset show that the proposed model achieves better sleep staging performance with less parameters compared with various baseline models. The overall accuracy

macro-averaging precision

macro-averaging recall

macro-averaging F1-score

and Cohen’s-kappa coefficient achieve 0.807

0.784

0.735

0.750

and 0.721

respectively. According to the performance comparisons of different feature encoding methods from three views and the visualization of attention weights

this paper further demonstrates the satisfied encoding ability and interpretability of proposed model. This study aims to provide innovative deep learning approaches and technologies for the research of sleep staging applications

thus assisting sleep experts to improve the efficiency of sleep disorder diagnosis and treatment.

关键词

Keywords

references

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