YU Li-ling, YANG Wei, LU Zhen-tai, et al. Joint Estimation of Enhancement Field Sequence and Deformation Field of Breast DCE-MRI[J]. Acta Electronica Sinica, 2014, 42(8): 1509-1514.
YU Li-ling, YANG Wei, LU Zhen-tai, et al. Joint Estimation of Enhancement Field Sequence and Deformation Field of Breast DCE-MRI[J]. Acta Electronica Sinica, 2014, 42(8): 1509-1514. DOI: 10.3969/j.issn.0372-2112.2014.08.008.
Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) suffer artifact by patient motion during the imaging procedure.It is necessary to correct patient motion by deformation registration for DCE-MRI.We present a MAP framework of joint estimation of the enhancement field sequence and the deformation field
which can make use of the prior knowledge of enhancement in space-time.The enhancement field sequence and the deformation field are modeled by the MRF models with the smoothness constraints
and are estimated by a two-step alternate optimization algorithm.In the alternate optimization procedure
the estimated enhancement field sequence is used to de-enhance the post-contrast images.Thus
the pre-contrast and post-contrast images can be considered as the same modal image for registration and it make the estimation of deformation field easier.The experimental results show that the proposed method can estimate the enhancement field sequence accurately and provides high registration accuracy.