本文对基于TSM的压电免疫传感器的起源进行了回顾,指出了Sauerbrey方程的局限性,分析、讨论了敏感膜粘弹特性、测试溶液的粘滞性以及测试溶液的电导率和介电常数对压电免疫传感器等效电路的影响,给出了压电免疫传感器在生物敏感膜和溶液共同作用下的等效电路,总结了此研究领域存在的问题及今后的发展方向.

The origin of the TSM-based piezoelectric immunosensors is reviewed in this paper.The limitation of the Sauerbrey equation is presented.The impact of the viscoelasticity of the sensitive film,the viscosity,conductivity and the dielectric constant of the testing fluid on the equivalent circuit is analyzed and discussed.The equivalent circuit under the bio-sensitive film and the fluid co-worked loading condition is shown.The remained problems and the future development trends in this research field are commented briefly.